As I've written before on my posts at the-sage.org, I'm not against the paleo diet - it's backed by a really shallow understanding of evolutionary theory and desperately needs a name change (Unprocessed/antigrain isn't very sexy, I guess), but overall, I don't see a huge worry for nutritional deficiencies - depending on the strictness/vigilance, an individual might be low in calcium, iodine, manganese and vitamin E. From a clinical perspective, I'm more concerned with those consuming standard American diets. From a scientific perspective, I'm mostly concerned with religious evangelization of a dietary mantra posing as science. I had a friend send me this link , claiming that gluten free diets are backed by 'real' science and asked me for my thoughts. For one, i'm familiar with Robb Wolfe, and generally like his and Matt LaLonde's call for a harder science approach to the Paleo movement. I am a big critic of the dietetics education standards...
Nutritional Sciences: Basic Science and Clinical Perspectives